The College of Physicians of Philadelphia


Gigantism

imageGigantism is different than being very tall. It is a medical condition most often caused by a problem with the pituitary gland. The pituitary gland is found at the base of the brain.  It releases chemicals called hormones that cause us to grow and develop.

Gigantism in children causes too much growth, particularly in the arms and legs.  Over production of growth hormone in adults who have stopped growing is called Acromegaly.

Acromegaly causes bone deformation. The jaw becomes larger and the brow ridges thicken.  The ribs stick out causing the individual to become barrel-chested.  In addition, the individual’s hands and feet become very large.

Both conditions have serious side effects including heart failure due to an enlarged heart. Individuals may also suffer from serious arthritis.

Many years ago these conditions were an early death sentence.  The Mütter Museum’s American Giant (pictured above) died in his early 20s. Today, these conditions are being diagnosed earlier and treated with surgery, radiation, and medication.  To get answers to all your gigantism questions, visit our list of Recommended Sites

To find support groups or treatment programs in Bucks, Chester, Delaware, Montgomery, or Philadelphia County, use our resource list in the blue box on the right side of the page.


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Department of Neurology and Neurosurgery - Hahnemann University Hospital
Department of Neurosurgery - Thomas Jefferson University Hospital
Department of Neurosurgery - University of Pennsylvania Health System

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